Both are cleared for caries, periapical radiolucency, calculus and bone level on bitewings and periapicals, both have a pediatric caries clearance (Overjet K233738, Pearl K243893), and both have a CBCT clearance that segments or marks anatomy rather than flagging disease (Overjet K251514, Pearl K243989). Pick Overjet if you want findings shown while you read the x-ray (its clearances are concurrent-read), bone level as a measurement (K210187), or charting of teeth and past restorations from x-rays (K241684, K261059). Pick Pearl if you want a second-opinion read after your own, disease findings on panoramic films (caries, periapical radiolucency and impacted third molars, K250525), or an integration with Curve Dental or CareStack. Neither publishes prices.
Overjet or Pearl: which should you choose?
- You want AI findings on screen while you read the x-ray, not after (concurrent-read clearances such as K222746 and K231678)
- Perio charting depends on bone level as a number (K210187)
- You want teeth, tooth numbers and past restorations charted from x-rays (Charting Assist K241684, Multi-Image K261059)
- You want a second opinion after your own read (Second Opinion K210365, K242522, K242600)
- You want caries, periapical radiolucency and impacted third molars flagged on panoramic films (K250525)
- Your practice runs Curve Dental or CareStack
What is each FDA-cleared for?
| Cleared for | Overjet | Pearl |
|---|---|---|
| Caries | Yes (K261059, K233738, K222746, K212519) | Yes (K250525, K243234, K243893, K242522, K210365) |
| Bone level | Yes (K210187) | Yes (K243230) |
| Calculus | Yes (K220928) | Yes (K210365) |
| Periapical radiolucency | Yes (K231678) | Yes (K250525, K242600, K210365) |
| CBCT anatomy, segmentation or viewing | Yes (K251514) | Yes (K243989) |
| Findings or charting on panoramic x-rays | Yes (K261059, K241684, K233590) | Yes (K250525) |
| Children | Yes (K261059, K233738) | Yes (K243893) |
| Charting & restorations | Yes (K261059, K241684, K233590) | No |
| Image enhancement | Yes (K241681) | No |
From each clearance's indications for use in the FDA 510(k) database. Full list: FDA-cleared dental AI companies.
Overjet vs Pearl: FDA clearances, price and integrations side by side
| Overjet | Pearl | |
|---|---|---|
| Vendor | Overjet, Inc. · Boston, MA | Pearl Inc. · Los Angeles, CA |
| Category | Imaging & diagnostics | Imaging & diagnostics |
| FDA 510(k) | K261059 (Aug 6, 2026); K253930 (Apr 10, 2026); K251514 (Dec 5, 2025); K241681 (Sep 9, 2024); K241684 (Aug 27, 2024); K233738 (Mar 4, 2024); K233590 (Feb 23, 2024); K231678 (Sep 21, 2023); K222746 (Mar 27, 2023); K220928 (Dec 16, 2022); K212519 (May 10, 2022); K210187 (May 19, 2021) | K250525 (Nov 14, 2025); K243234 (Jun 12, 2025); K243989 (May 23, 2025); K243230 (May 9, 2025); K243893 (May 5, 2025); K242600 (Apr 11, 2025); K242522 (Jan 16, 2025); K210365 (Mar 4, 2022) |
| Cleared for | Multi-Image Caries and Charting Assist: reads all of a patient's radiographs together. Detects and outlines caries (incipient, non-incipient, secondary) on bitewings and periapicals, and tooth anatomy, tooth numbers and past restorations on bitewing, periapical and panoramic radiographs, patients 4 and older. / Web-based image management (PACS): acquires, stores, displays and shares dental images from intraoral sensors and panoramic units. / AI segmentation, measurements and 2D/3D visualization of dental and craniomaxillofacial CBCT scans. / Image Enhancement Assist: AI noise reduction and contrast/sharpness enhancement of dental radiographs in the Overjet platform. / Charting Assist (updated): detects tooth anatomy, tooth numbers and existing restorations (implants, crowns, root canals, fillings) to assist charting. / Caries Assist-Pediatric: concurrent-read caries detection and segmentation on bitewing and periapical radiographs in children. / Charting Assist: detects tooth anatomy, tooth numbers and existing restorations to assist dental charting. / Periapical Radiolucency Assist: concurrent-read detection of periapical radiolucencies on periapical radiographs, permanent teeth. / Caries Assist (expanded): concurrent-read caries detection and segmentation on bitewing and periapical radiographs. / Calculus Assist: concurrent-read detection of interproximal calculus on bitewing and periapical radiographs. / Caries Assist: concurrent-read detection of caries on bitewing radiographs. / Dental Assist: automated measurement of alveolar bone level on bitewing and periapical radiographs. | Marks suspected caries, periapical radiolucency and impacted third molars on panoramic radiographs, patients 16 and older. / Second Opinion CS: detection and segmentation of caries on periapical radiographs, permanent teeth, patients 12 and older (second reader). / Second Opinion 3D: marks anatomy on CBCT (dentition, maxilla, mandible, inferior alveolar canal, sinus, airway). / Second Opinion BLE: bone-level measurements on bitewing and periapical radiographs, patients 12 and older. / Second Opinion Pediatric: caries detection on bitewing and periapical radiographs, patients 4 and older (primary or mixed dentition). / Periapical radiolucency detection with outlined regions on periapical radiographs, permanent teeth, patients 12 and older (second reader). / Second Opinion CC: caries detection with outlined regions on bitewing and periapical radiographs, patients 19 and older (second reader). / Second Opinion: detection of caries, calculus, periapical radiolucency and other findings on bitewing and periapical radiographs. |
| Imaging modalities | bitewing, periapical, panoramic, CBCT | bitewing, periapical, panoramic, CBCT |
| Pricing | Not published (contact sales) | Not published (contact sales) |
| Integrations | Dentrix, Eaglesoft, Open Dental | Eaglesoft, Dentrix, Open Dental, Curve Dental, Carestack |
| Best fit | solo, group, dso, perio | group, dso |
| Last verified | Oct 22, 2026 | Oct 22, 2026 |
From each vendor's site and the FDA 510(k) database.
Strengths and limits
- Quantitative bone level and caries probability scores, not just detection flags
- Integrates with the PMS systems most dental practices already use
- Supports insurance pre-authorization with objective data
- Enterprise pricing model may not fit solo or small group practices
- Caries, calculus, periapical and restoration findings in a single clearance (K210365)
- Widest PMS integration coverage, working with 5+ major systems
- Practice Intelligence adds business analytics on top of clinical detection
- Enterprise pricing model; cost unclear until sales conversation
- Detection accuracy is condition-dependent, strongest on caries, weaker on marginal bone loss
Next steps
Common questions
What is the difference between Overjet and Pearl?
Both are cleared for caries, periapical radiolucency, calculus and bone level on bitewings and periapicals, both have a pediatric caries clearance (Overjet K233738, Pearl K243893), and both have a CBCT clearance that segments or marks anatomy rather than flagging disease (Overjet K251514, Pearl K243989). Pick Overjet if you want findings shown while you read the x-ray (its clearances are concurrent-read), bone level as a measurement (K210187), or charting of teeth and past restorations from x-rays (K241684, K261059). Pick Pearl if you want a second-opinion read after your own, disease findings on panoramic films (caries, periapical radiolucency and impacted third molars, K250525), or an integration with Curve Dental or CareStack. Neither publishes prices.
Which is FDA cleared, Overjet or Pearl?
Overjet: K261059, K253930, K251514, K241681, K241684, K233738, K233590, K231678, K222746, K220928, K212519, K210187. Pearl: K250525, K243234, K243989, K243230, K243893, K242600, K242522, K210365. Check the scope of each clearance; features outside it are not cleared.
Is Overjet or Pearl cleared for panoramic x-rays?
Both, for different things. Pearl's K250525 flags suspected caries, periapical radiolucency and impacted third molars on panoramic films for patients 16 and older. Overjet's panoramic coverage is for charting: tooth anatomy, tooth numbers and past restorations (Charting Assist K241684, Multi-Image K261059).
Are Overjet and Pearl cleared for children?
Yes. Overjet Caries Assist-Pediatric (K233738) covers caries on bitewings and periapicals in children, and Multi-Image Caries and Charting Assist (K261059) starts at age 4. Pearl's Second Opinion Pediatric (K243893) covers caries on bitewings and periapicals from age 4, with primary or mixed teeth.
Can Overjet or Pearl read CBCT scans?
Both have one CBCT clearance, and neither flags disease on CBCT. Overjet CBCT Assist (K251514) covers AI segmentation, measurements and 2D/3D viewing. Pearl Second Opinion 3D (K243989) marks anatomy such as the dentition, jaws, inferior alveolar canal, sinus and airway.