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Independent. No vendor sponsorships.Editorial policyCorrectionsUpdated Oct 21, 2026
AI Dental ToolsThe independent reference for AI in dental practice
Bottom line

Same vendor, different products. Dentrix is server-based and runs in your office. Dentrix Ascend is cloud-based, with AI image checks, AI dictation, instant eligibility and VideaHealth detection built into its packages. Moving between them is a data conversion, not an upgrade.

Side by side

DentrixDentrix Ascend
VendorHenry Schein One · American Fork, UTHenry Schein One · American Fork, UT
CategoryPractice managementPractice management
FDA 510(k)None confirmedNone confirmed
Cleared for——
Imaging modalities——
PricingNot published (Quote: license plus support plan)Not published (Quote: monthly subscription by package)
IntegrationsDentrix Imaging, VideaHealth (Detect AI), Most imaging bridges and third-party eServicesVideaHealth (AI radiograph detection), Ascend Imaging
Best fitsolo, groupgroup, dso, solo
Last verifiedOct 21, 2026Oct 21, 2026
Choose Dentrix if
  • You have one location and a reliable server
  • Your team relies on Dentrix workflows and third-party bridges
  • You want to avoid a conversion
Choose Dentrix Ascend if
  • You want no server and access from anywhere
  • You run several locations and want shared reporting
  • You want AI dictation, image checks and eligibility built in
Dentrix: strengths and limits
  • Largest installed base: most staff have used it and most vendors integrate with it
  • Deep feature set for insurance-heavy general practices
  • AI (Detect AI) and eligibility add-ons from the same vendor
  • Server-based: the practice manages the server, backups and remote access
  • Pricing is not published, and add-ons are sold separately
  • Multi-location groups often move to Dentrix Ascend or another cloud system
Dentrix Ascend: strengths and limits
  • Cloud system from the largest PMS vendor, with AI built in rather than bolted on
  • Good fit for multi-location groups that want shared reporting
  • Online booking, forms and eligibility are native
  • A different product from Dentrix: moving from Dentrix still means a data conversion and retraining
  • Package pricing is not public

Common questions

What is the difference between Dentrix and Dentrix Ascend?

Same vendor, different products. Dentrix is server-based and runs in your office. Dentrix Ascend is cloud-based, with AI image checks, AI dictation, instant eligibility and VideaHealth detection built into its packages. Moving between them is a data conversion, not an upgrade.

Which is FDA cleared, Dentrix or Dentrix Ascend?

Dentrix: no clearance confirmed. Dentrix Ascend: no clearance confirmed. Check the scope of each clearance; features outside it are not cleared.